Electrospun Materials in Neuroscience
Our Mimetix® Aligned fibres (TECL 006) were once again used as a pivotal tool to study oligodendrocytes in vitro. Oligodendrocytes produce myelin which plays a key role in the signal transduction by neurons. These oligodendrocytes exist in different populations and the authors investigated whether the location of these various populations correlates with their function. Published… Read more »
High-throughput quantification
Nature Communications paper “Deep learning for high-throughput quantification of oligodendrocyte ensheathment at single-cell resolution” by a team at McGill university describes how they established a high-throughput method to assess oligodendrocyte ensheathment in-vitro, combining nanofiber culture devices and automated imaging with a heuristic approach that informed the development of a deep learning analytic algorithm.This is important because… Read more »
Multiple sclerosis repair roadmap
Research published in the journal Nature provides new understanding about how drugs can repair damaged brain cells that cause disability in patients with multiple sclerosis. Led by researchers at Case Western Reserve University School of Medicine, the study suggests new drug targets and potent early-stage drug candidates could lead to regenerative medicines for multiple sclerosis… Read more »
