Description

Product Description

The Mimetix^® 384-well plate, our highly-consistent and easy-to-use 3D platform, holds great promise to reduce the number of costly drug failures in clinical trials, enabling more realistic tumour and toxicology models. The Mimetix scaffold is incorporated into a standard 384-well plate frame with a base having superior optical clarity, which provides minimal base distortion and avoids the use of glues. The scaffold depth of 50 μm is thick enough to provide the benefits of 3D cell morphology and behaviour yet thin enough to allow microscopic imaging.

General Features:

• True 3D environment rather than a roughened 2D surface.
• Minimal protocol adaption required to switch from 2D to 3D.
• Compatible with industry-standard automated handling and imaging equipment.

Scaffold Specifications:

• Material: medical-grade poly-L-lactide (PLLA)
• Scaffold thickness: 50 μm
• Fibre diameter: 4 μm
• Pore size: 15-30 μm
• Overall porosity: app. 80%
• Non-biodegradable in in vitro applications
• Supplied with lid

Usage & Handling:

• Compatible with fluorescence microscopy.
• Supplied gamma-irradiated in individually-sealed plastic wrapping.
• Scaffolds can be coated with materials to facilitate cell adhesion in low serum conditions.
• Cells can be removed from the Mimetix^® scaffold by trypsinisation and gentle agitation.
• Protocols for cell seeding, assays, and imaging are available in our Technical Support section.
• Store at room temperature in the dark.

Download the specification sheet: TECL-001 Mimetix 384-well plate v5.0