Mimetix® electrospun scaffolds

The Electrospinning Company manufactures a range of scaffolds that are available in standard well-plate format. Mimetix scaffolds are manufactured from GMP-grade poly-L-lactide polymer (PLLA) with tight control over key parameters such as fibre diameter and thickness. The laboratory consumable products are highly consistent providing researchers reliable tools for reproducible cell-based assays. They are provided irradiated with gamma or e-beam.

For more details on the product range click here.

To Purchse Mimetix Product contact our Distributor AMS Biotechnology. 

Composite scaffold of PLLA and courtesy of Dr Raghavendran, University of Malaya
Liver cancer cells (HepG2) grown for 21 days in Mimetix scaffold

Randomly orientated Mimetix® scaffold

Mimics the extracellular matrix while providing a true 3D environment for the cells to grow. Evaluated with a range of immortalised cell lines, primary cells and stem cells. Applications include: non weight-bearing; bone regeneration; corneal repair; hepatotoxicity assays; cancer cell assays.

Mimetix standard scaffold dimensions:

  • Fibre diameter of 4 microns
  • Pore size of 15-30 microns, porosity of around 80%
  • Depth of 50 microns

Available formats:

  • 12-well plate with loose scaffolds and retaining rings (TECL-003)
  • Sheets or discs (to order)
  • Microscaffolds (to order)
TECL003 Mimetix 12-well plate with removable scaffold discs
Randomly aligned fibres
Schwann cells grown for 21 days, courtesy of Dr Bechler, Centre for Regenerative Medicine, Edinburgh

Aligned Mimetix® scaffold

Ideal for cells needing physical guidance and/or where cellular orientation influences cell behaviour and function.Evaluated with a range of primary cells and stem cells. Applications include: oligodendrocytes and myelination assays, Schwann cells, nerve conduit repair, tendon repair, cardiomyocytes, cardiotoxicity.

Mimetix aligned scaffold standard dimensions:

  • Fibre diameter of 2 microns
  • Depth of 2-4 microns

Available formats:

  • Crown cell inserts in 12 well plates (TECL006)
TECL006 Mimetix Aligned crown cells inserts in 12-well plate
Aligned fibres
Cardiomyocytes grown for 12 days on Aligned Mimetix scaffolds, courtesy of Dr Trepakova, Merck, USA

Extra porous Mimetix® air scaffold

Ideal for flow and bioreactor applications. Evaluated for stem cell (iPS and hESC) proliferation and differentiation.

Mimetix Air standard dimensions:

  • Fibre diameter of 7-8 microns
  • Porosity of over 90%
  • Depth of up to 3.5 mm

Available format: Discs or in well plate formats

Highly porous Mimetix air scaffold
Cross section of 2.5 mm scaffold showing complete penetration with muscle satellite cells, courtesy of Dr Chotteau, KTH, Sweden

Mimetix products can be purchased from AMS biotechnology.