Polymer Combinations

In a new publication titled “A synergistic relationship between PCL and natural polymers enhances the physical properties and biological activity of scaffolds”, researchers at RAFT have shown the versatility of our Mimetix Air® scaffolds to be combined with natural polymer such as collagen, elastin and fibrin, with industrially applicable production methods.

Their work shows how the physical as well as biological properties of Mimetix Air® scaffolds can be controlled with the addition of natural polymers. Through this addition it was possible to tailor the swelling behaviour, hydrophilicity, porosity, mechanical properties, and rate of degradation. Through these changes the authors show that human adipose-derived stem cells (hADSCs) seeded onto different types of scaffolds exhibited changes in angiogenesis and cell-material interactions. Scaffolds with natural polymers also showed persistent levels of myogenic and adipogenic markers.

If you want to explore the potential of Mimetix Air® you can find more information here or contact us at info@electrospinning.co.uk.

Original Source: Sawadkar, P. et al. A Synergistic Relationship between Polycaprolactone and Natural Polymers Enhances the Physical Properties and Biological Activity of Scaffolds. ACS Applied Materials & Interfaces 12, 13587–13597 (2020). doi:https://doi.org/10.1021/acsami.9b19715