Mimetix® scaffolds were used in the recent publication “Phase-contrast 3D tomography of HeLa cells grown in PLLA polymer electrospun scaffolds using synchrotron X-rays” in The Journal of Synchrotron Radiation. This study, led by a team at the University College London (UCL), collaborating with the Research Centre at Harwell (RCAH) and Diamond Light Source on the Harwell Innovation Campus, investigated the use of synchrotron x-ray method to determine the growth of cells in 3D structures. Mimetix® scaffolds are made of electrospun poly l-lactide (PLLA) and are used for cell culture and tissue engineering applications. The team compared two fibre diameters, including 4 microns which is used in commercially available Mimetix products, and examined cell infiltration and cell-cell connectivity over 2, 5 and 8 days. This investigation shows the potential of Mimetix® plates to study complex behaviour of cells in 3D and the potential for imaging technology to study cell-scaffold interactions for future medical use.
You can read more publication on electrospinning method used for tissue engineering applications here.