The Electrospinning Process

The Electrospinning Process

Electrospinning is an established method of producing nanofibres from a wide variety of natural and synthetic polymers. A polymer solution is injected at a constant feed rate though a nozzle or needle which is charged to a high voltage, typically 10 to 30 kV. The applied voltage induces a charge on the surface of the liquid droplet and when this is sufficiently high, the hemispherical surface of the fluid elongates and a Taylor cone is established. On increasing the applied voltage further, a charged liquid jet is ejected from the Taylor cone and attracted to the earthed collector, which is positioned at a fixed distance from the needle. During this process the solvent evaporates from the polymer solution, leaving dry polymer fibres on the collector.

Click on the image below to see the electrospinning process in action. First start the solution and then start the voltage.

 

The Electrospinning Process

Copyright 2005 Michigan Technological University. Used with permission.

 

Electrospun fibre scaffolds for 3D cell culture

The Electrospinning Company uses sophisticated electrospinning equipment and proprietary know-how in manufacturing methods and polymer chemistry to guarantee batch-to-batch reproducibility and precisely control important fibre parameters, such as diameter and surface texture. We are differentiated in our ability to produce highly consistent, reproducible scaffolds that are suitable for cell culture and laboratory research, and ultimately transferable for use in clinical applications. Each scaffold batch is checked under a scanning electron microscope (SEM) before shipment to the customer.

 

Fibre diameter distribution of our electrospun fibres

SEM image (left) of our highly uniform electrospun fibres at 2000x magnification and corresponding fibre diameter distribution (right), showing a relative standard deviation of only 8.5%.