The Electrospinning Process

Electrospinning is an established method of producing nano- and micro-fibres from a wide variety of natural and synthetic polymers. A polymer solution is injected at a constant feed rate though a nozzle or needle which is charged to a high voltage, typically 10 to 30 kV. The applied voltage induces a charge on the surface of the liquid droplet and when this is sufficiently high, the hemispherical surface of the fluid elongates and a Taylor cone is established. On increasing the applied voltage further, a charged liquid jet is ejected from the Taylor cone and attracted to the earthed collector, which is positioned at a fixed distance from the needle. During this process the solvent evaporates from the polymer solution, leaving dry polymer fibres on the collector.

Electrospinning for 3D cell culture and Biomaterials

  • Electrospun nano- and micro- fibres mimic the natural extracellular matrix and provide an ideal substrate for adherent cells.
  • Fibres can be oriented in different alignments to promote the growth and differentiation of different cell types.
  • The porous architecture (>80-95%) of electrospun scaffolds facilitates efficient nutrient exchange and extraction of expression markers.
  •  Scaffolds can be synthesised from medical-grade polymers without animal-derived products.
  • Scaffolds can be tuned to degrade over time, or not.

What makes us special?

We use sophisticated electrospinning equipment and proprietary know-how in manufacturing methods and polymer chemistry to guarantee batch-to-batch reproducibility and precisely control important fibre parameters, such as diameter and surface texture.

The electrospinning process is notoriously sensitive to multiple factors. We are focused on the production of highly consistent scaffolds, and this reproducibility makes them suitable for clinical applications and scalable.

The quality of each scaffold batch is checked for a range of specifications, agreed with the customer, including fibre diameter, pore size, porosity, thickness, mechanical properties and residual solvent.

We produce all our material in a Class V cleanroom using state-of-the art electrospinning equipment and are ISO 13485 certified.