We have extensive scaffold design and manufacturing capabilities to develop bespoke scaffolds from a variety of polymers and in custom formats. The porosity and stiffness/ flexibility of the scaffold can be adjusted to meet customer requirements.The following parameters can be adjusted:
Scaffolds can be made of biodegradable polymers, such as PLLA, PLGA, PCL, PVDF. Other biocompatible polymers are available; please enquire for further information.
We can produce fibres with diameters ranging from 500 nm to about 5 μm. The larger the fibre diameter, the larger the pores.
Available thicknesses range from 50 μm to 200 μm.
Multilayer or mixed membranes
Membranes consisting of more than one layer can be fabricated, for example using different polymers or altering fibre diameter, pore size distribution, or layer thickness.
Incorporation of bioactive materials
This includes scaffolds made of natural polymers, uniform protein coatings, or incorporation of drugs or other bioactive substances; please enquire for further information.
Advanced Fibre Technologies
Co-axial (concentric) Fibres
For applications such as drug delivery, fibres made from two different polymers or polymer blends can be made such that one or both of the layers in the fibre release the bio-active material at a pre-defined rate.
Classical electrospinning produces randomly orientated fibres. We can also manufacture aligned fibres using high speed rotating collectors. Applications include the production of scaffolds which mimic aligned fibres found in the spinal cord and in the human eye.
In addition to nanofibres, we can produce nanocoatings using the related process of electrospray to coat three dimensional objects.
To add specific features to the scaffold.
Spinning onto 3D shapes
Besides the production of membranes and disks for cell culture dishes, we can produce custom 3D formats, such as self-supporting tubes, composite tubes and other 3D shapes.
Please contact us if you would like to discuss the development of electrospun scaffolds for your specific application.