The electrospinning process can be used to create synthetic scaffolds for implantation. The advantages of this process are the ability to tailor polymer, architecture and structure to create materials suitable for different therapeutic applications.
Polymer Raw Materials
We work with a range of polymers to tailor mechanical properties, such as stiffness and elasticity, as well as degradation rate to different cell types and applications. Where possible we use polymers which have previously been used in medical devices with regulatory documentation.
- Poly Lactides (PLA) – stiff materials (Young’s modulus GPa range) with degradation rates longer than 3 years
- Poly Lactide Glycolides (PLGA) – stiff materials that can be tuned to degrade over periods of four weeks to 18 months
- Poly Caprolactone (PCL) – softer material (Young’s modulus 100s of MPa range) that can be tuned to degrade over two to three years
- Poly(lactide-co-caprolactone) (PLCL) – elastic material (Young’s modulus 10s of MPa range) that can be tuned to degrade in vivo over 6-18 months
- Polyacrylonitrile (PAN) – Stiff material which does not degrade