We have extensive scaffold design and manufacturing capabilities to develop bespoke scaffolds from a variety of polymers and in custom formats.
Random vs. aligned
Classical electrospinning produces randomly orientated fibres, as in our Mimetix scaffold. We can also manufacture aligned fibres using high speed rotating collectors. Aligned fibres can support the differentiation of cells which require a particular orientation, such as peripheral nerves and tendons.
Polymers & biodegradability
Our Mimetix scaffold is made of the FDA-approved, biocompatible polymer PLLA. A range of other polymers is available, including biodegradable polymers (PLGA, PCL) and non-biodegradable polymers (e.g. polyurethanes). Please enquire for further information.
Fibre diameter
We can produce fibres with diameters ranging from 500 nm to about 5 μm. The larger the fibre diameter, the larger the pores.
Scaffold/Membrane thickness
Standard thicknesses available are 50 μm and 100 μm. However, we can fabricate both thinner and thicker materials. Please contact us to discuss your individual requirements.
Multilayer or mixed membranes
Membranes consisting of more than one layer can be fabricated, for example using different polymers or altering fibre diameter, pore size distribution, or layer thickness.
Incorporation of bioactive materials and coatings
We can incorporate bioactive substances, such as therapeutic agents, into electrospun scaffolds. In addition, we can coat scaffolds with proteins and epitopes to enhance cell adhesion. Please enquire for further information.
Spinning onto 3D shapes
Besides the production of membranes and disks for cell culture dishes, we can produce custom 3D formats, such as self-supporting tubes, composite tubes and other 3D shapes.
