Bespoke Products

We have extensive scaffold design and manufacturing capabilities to develop bespoke scaffolds from a variety of polymers and in custom formats.

 

Random vs. aligned

Classical electrospinning produces randomly orientated fibres, as in our Mimetix scaffold. We can also manufacture aligned fibres using high speed rotating collectors. Aligned fibres can support the differentiation of cells which require a particular orientation, such as peripheral nerves and tendons.

Random vs. aligned scaffolds

 

Polymers & biodegradability

Our Mimetix scaffold is made of the FDA-approved, biocompatible polymer PLLA. A range of other polymers is available, including biodegradable polymers (PLGA, PCL) and non-biodegradable polymers (e.g. polyurethanes). Please enquire for further information.

Electrospun scaffolds made of different polymers

 

Fibre diameter

We can produce fibres with diameters ranging from 500 nm to about 5 μm. The larger the fibre diameter, the larger the pores.

Fibre diameters
 

Scaffold/Membrane thickness

Standard thicknesses available are 50 μm and 100 μm. However, we can fabricate both thinner and thicker materials. Please contact us to discuss your individual requirements.

 

Multilayer or mixed membranes

Membranes consisting of more than one layer can be fabricated, for example using different polymers or altering fibre diameter, pore size distribution, or layer thickness.

 

Incorporation of bioactive materials and coatings

We can incorporate bioactive substances, such as therapeutic agents, into electrospun scaffolds. In addition, we can coat scaffolds with proteins and epitopes to enhance cell adhesion. Please enquire for further information.

 

Spinning onto 3D shapes

Besides the production of membranes and disks for cell culture dishes, we can produce custom 3D formats, such as self-supporting tubes, composite tubes and other 3D shapes.

 

Stent coated with electrospun fibre

Stent coated with electrospun fibre

 
 

Please contact us if you would like to discuss the development of electrospun scaffolds for your specific application.